Fluorescence Lifetime Microscope (S)FLIM / FCS / FRET TauMap
Description
The MPTflex is a CE-certified medical tomograph based on femtosecond multiphoton excitation of fluorescent biomolecules like NAD(P)H, flavins, porphyrins, elastin, and melanin. The extracellular matrix protein collagen can be identified by its second harmonic generation (SHG). Autofluorescence and SHG signals are recorded by fast PMT detectors with single photon sensitivity.
The tomograph consists of a compact, turn-key tunable femtosecond near
infrared (NIR) laser, an articulated arm with NIR optics, a beam- scanning module with galvoscanners and piezo -driven optics, a two-PMT-detector module as well as a control unit including JenLab Image software for image processing. An additional module for two-photon in-vivo FLIM as well as two-photon microendoscopy can be provided.
Fluorescence Lifetime Microscope (S)FLIM / FCS / FRET TauMap
Specifications |
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|---|---|
| Scan Range (X): | 350 um |
| Scan Range (Y): | 350 um |
| Scan Range (Z): | 200 um |
| Spatial Resolution (lateral): | 1 um |
| Spatial Resolution (vertical): | 2 um |
Applications
The major application is early diagnosis of skin diseases such as malignant melanoma. Using innovative non-invasive multiphoton technology the physician obtains optical biopsies with detailed information on living cells and tissue structures within their physiological environment. Dermatological disorders can be detected with submicron spatial resolution. The image acquisition time is less than 20 seconds per frame. The novel tomograph MPTflex has the potential to revolutionize the conventional invasive time consuming diagnostic procedures. The multiphoton tomograph can also be used in tissue engineering and wound healing studies as well as in cosmetic and pharmaceutical research.
The efficiency of anti-aging products as well as the biosafety of sunscreen nanoparticles can be tested in vivo. Furthermore, the skin age can be evaluated by measuring the ratio of elastin to collagen.
- intra-vital imaging of molecular and ion dynamic
- Visualization of protein interactions in living cells
- Second harmonic and fluorescence microscopy
- Fluorescence lifetime imaging (FLIM)
- Fluorescence resonance energy transfer (FRET)
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How to order?
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Ships from:
Germany
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Frequently Asked Questions
The MPTflex tomograph is used for early diagnosis of skin diseases such as malignant melanoma, tissue engineering and wound healing studies, and in cosmetic and pharmaceutical research.
The TauMapTM imaging system offers submicron spatial and subnanosecond temporal resolution.
The TauMapTM imaging system includes JenLab scan software and SPC image data analysis software for data acquisition and image processing.
The MPTflex tomograph offers second harmonic and fluorescence microscopy, fluorescence lifetime imaging (FLIM), fluorescence resonance energy transfer (FRET), and fluorescence correlation spectroscopy (FCS).
The MPTflex tomograph is based on femtosecond multiphoton excitation of fluorescent biomolecules like NAD(P)H, flavins, porphyrins, elastin, and melanin.